<html>
<body>
<form>
<select id="mySelect" size="4">
<option>Apple</option>
<option>Pear</option>
<option>Banana</option>
<option>Orange</option>
</select>
</form>
<br>
<button onclick="myFunction()">Remove last option</button>
<script>
function myFunction() {
var x = document.getElementById("mySelect");
if (x.length > 0) {
x.remove(x.length-1);
}
}
</script>
</body>
</html>